How Ketamine-Assisted Therapy Offers Hope

By Ali McGhee, Lucid News

As interest in ketamine as a mental health treatment continues to grow, what should therapists know about this drug with a long history of off-label use, and how can they begin their own training in ketamine-assisted psychotherapy (KAP)?

Psychedelic therapy effective in reducing suicidality, more trials needed

Journal of Clinical Psychiatry

Psychedelic therapy appeared associated with large acute and sustained reductions in suicidality, according to results of a meta-analysis published in the Journal of Clinical Psychiatry

The study’s authors aimed to fill a knowledge gap regarding psychedelic therapy and effects on suicidality. “Suicide is a global health concern and innovative interventions that target suicidality are needed,” they wrote.

How do psychedelics treat depression: The potential role of neuroplasticity

World Journal Psychiatry

This literature review analyzes possible mechanisms of action for ketamine as an antidepressant. Traditional antidepressants often take weeks to months to work and are not effective for all patients. This review specifically compares the effects of serotonergic psychedelics with other antidepressants on plasticity at multiple levels of nervous system functioning.

Ketamine-Assisted Psychotherapy versus Ketamine Infusion

Journal of Psychoactive Drugs

Read one of the first studies on the emerging Ketamine-Assisted Psychotherapy model as it compares to the medical model of the Ketamine Infusion Clinic. One of the most interesting contentions between the two models is that Ketamine-Assisted Psychotherapy maintains that the psychedelic experience itself is an irreducible catalyst for the antidepressant effects of ketamine, while the Ketamine Infusion Clinic seeks to minimize the psychedelic experience (by controlling dose over time), seeking instead to get the antidepressant effect without the psychedelic experience.

5 Most Important Psychedelic Clinical Trials in 2022

Psychedelic Spotlight

These MDMA, psilocybin, LSD, DMT and ketamine clinical trials may have huge impacts on the entire psychedelic medicine industry. 

Ketamine Therapy is Going Mainstream: Are We Ready?

By Emily Witt, The New Yorker

The mind-altering drug Ketamine has been shown to help people suffering from anxiety and depression. But how it helps, who it will serve, and who will profit are open questions.

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